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Statins inhibit cholesterol biosynthesis at the initial mevalonic acid level, while fibrates modify lipids, decrease triglycerides, and alter cholesterol levels of HDL/LDL by activating alpha peroxisome proliferator-activated receptors (PPAR-α)
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We were also able to show that pyocyanin-mediated oxidative stress in A549 cells can be reduced considerably by regular (daily) treatment with GSH ( Figure 8 ) and this likely facilitates the A549 cell growth seen in Figure 7
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